Foods and Raw Materials Foods and Raw Materials Foods and Raw Materials 2308-4057 2310-9599 64999 10.21603/2308-4057-2024-1-588 Review Article Review Article Review Article Nanoparticles of metals and their compounds in films and coatings: A review Nanoparticles of metals and their compounds in films and coatings: A review https://orcid.org/0000-0002-9632-6296 Eremeeva Natalia B. Eremeeva Natalia B. eremeeva.itmo@gmail.com ITMO University St. Petersburg Россия ITMO University St. Petersburg Russian Federation 13 02 2024 13 02 2024 12 1 60 79 02 11 2022 10 01 2023 https://jfrm.ru/en/issues/21683/21688/

Nanotechnology is important in food packaging because it increases shelf life, enhances food safety, and improves sensory characteristics and nutrient availability. We aimed to review scientific publications on the synthesis of nanoparticles, as well as their properties and applications in the food industry. Research and review articles published from 2020 to 2022 were obtained from the database using the keywords “nanoparticles”, “film”, and “food”. They were on the synthesis of metal and metal oxide nanoparticles and their uses in food films and coatings. We reviewed methods for synthesizing inorganic nanoparticles from metals and their compounds (silver, zinc, iron, etc.), as well as described their antimicrobial action against foodborne pathogens. By incorporating nanoparticles into films, we can create new materials with strong antimicrobial properties in vitro. Nanoparticles can be used to develop both polymer and biopolymer films, as well as their mixtures. Composite coatings can work synergistically with metal nanoparticles to create multifunctional food packaging systems that can act as compatibilizers. Particular attention was paid to metal nanoparticles in food coatings. We found that nanoparticles reduce the rate of microbial spoilage and inhibit lipid oxidation, thereby increasing the shelf life of raw materials and ready-to-eat foods. The safety of using nanoparticles in food coatings is an important concern. Therefore, we also considered the migration of nanoparticles from the coating into the food product. Incorporating nanoparticles into polymer and biopolymer films can create new materials with antimicrobial properties against foodborne pathogens. Such composite films can effectively extend the shelf life of food products. However, the undesirable migration of metal ions into the food product may limit the use of such films.

Nanotechnology is important in food packaging because it increases shelf life, enhances food safety, and improves sensory characteristics and nutrient availability. We aimed to review scientific publications on the synthesis of nanoparticles, as well as their properties and applications in the food industry. Research and review articles published from 2020 to 2022 were obtained from the database using the keywords “nanoparticles”, “film”, and “food”. They were on the synthesis of metal and metal oxide nanoparticles and their uses in food films and coatings. We reviewed methods for synthesizing inorganic nanoparticles from metals and their compounds (silver, zinc, iron, etc.), as well as described their antimicrobial action against foodborne pathogens. By incorporating nanoparticles into films, we can create new materials with strong antimicrobial properties in vitro. Nanoparticles can be used to develop both polymer and biopolymer films, as well as their mixtures. Composite coatings can work synergistically with metal nanoparticles to create multifunctional food packaging systems that can act as compatibilizers. Particular attention was paid to metal nanoparticles in food coatings. We found that nanoparticles reduce the rate of microbial spoilage and inhibit lipid oxidation, thereby increasing the shelf life of raw materials and ready-to-eat foods. The safety of using nanoparticles in food coatings is an important concern. Therefore, we also considered the migration of nanoparticles from the coating into the food product. Incorporating nanoparticles into polymer and biopolymer films can create new materials with antimicrobial properties against foodborne pathogens. Such composite films can effectively extend the shelf life of food products. However, the undesirable migration of metal ions into the food product may limit the use of such films.

 Nanoparticles antibacterial effect film coating packaging food products Nanoparticles antibacterial effect film coating packaging food products This study was financially supported by the Russian Science Foundation (RSF) (project No. 23-26-00056). This study was financially supported by the Russian Science Foundation (RSF) (project No. 23-26-00056).

Chesnokova NYu, Prikhodko YuV, Kuznetsova AA, Kushnarenko LV, Gerasimova VA. Anthocyanin films in freshness assessment of minced fish. Food Processing: Techniques and Technology. 2021;51(2):349-362. (In Russ.). https://doi.org/10.21603/2074-9414-2021-2-349-362 Chesnokova NYu, Prikhodko YuV, Kuznetsova AA, Kushnarenko LV, Gerasimova VA. Anthocyanin films in freshness assessment of minced fish. Food Processing: Techniques and Technology. 2021;51(2):349-362. (In Russ.). https://doi.org/10.21603/2074-9414-2021-2-349-362 Bhargava N, Sharanagat VS, Mor RS, Kumar K. Active and intelligent biodegradable packaging films using food and food waste-derived bioactive compounds: A review. Trends in Food Science and Technology. 2020;105:385-401. https://doi.org/10.1016/j.tifs.2020.09.015 Bhargava N, Sharanagat VS, Mor RS, Kumar K. Active and intelligent biodegradable packaging films using food and food waste-derived bioactive compounds: A review. Trends in Food Science and Technology. 2020;105:385-401. https://doi.org/10.1016/j.tifs.2020.09.015 Koosha M, Hamedi S. Intelligent Chitosan/PVA nanocomposite films containing black carrot anthocyanin and bentonite nanoclays with improved mechanical, thermal and antibacterial properties. Progress in Organic Coatings. 2019;127:338-347. https://doi.org/10.1016/j.porgcoat.2018.11.028 Koosha M, Hamedi S. Intelligent Chitosan/PVA nanocomposite films containing black carrot anthocyanin and bentonite nanoclays with improved mechanical, thermal and antibacterial properties. Progress in Organic Coatings. 2019;127:338-347. https://doi.org/10.1016/j.porgcoat.2018.11.028 Gubitosa J, Rizzi V, Lopedota A, Fini P, Laurenzana A, Fibbi G, et al. One pot environmental friendly synthesis of gold nanoparticles using Punica Granatum Juice: A novel antioxidant agent for future dermatological and cosmetic applications. Journal of Colloid and Interface Science. 2018;521:50-61. https://doi.org/10.1016/j.jcis.2018.02.069 Gubitosa J, Rizzi V, Lopedota A, Fini P, Laurenzana A, Fibbi G, et al. One pot environmental friendly synthesis of gold nanoparticles using Punica Granatum Juice: A novel antioxidant agent for future dermatological and cosmetic applications. Journal of Colloid and Interface Science. 2018;521:50-61. https://doi.org/10.1016/j.jcis.2018.02.069 Rolima WR, Pelegrinoa MT, de Araújo Lima B, Ferraza LS, Costa FN, Bernardesd JS, et al. Green tea extract mediated biogenic synthesis of silver nanoparticles: Characterization, cytotoxicity evaluation and antibacterial activity. Applied Surface Science. 2019;463:66-74. https://doi.org/10.1016/j.apsusc.2018.08.203 Rolima WR, Pelegrinoa MT, de Araújo Lima B, Ferraza LS, Costa FN, Bernardesd JS, et al. Green tea extract mediated biogenic synthesis of silver nanoparticles: Characterization, cytotoxicity evaluation and antibacterial activity. Applied Surface Science. 2019;463:66-74. https://doi.org/10.1016/j.apsusc.2018.08.203 Piñón-Segundo E, Mendoza-Muñoz N, Quintanar-Guerrero D. Nanoparticles as dental drug-delivery systems. In: Subramani K, Ahmed W, editors. Nanobiomaterials in clinical dentistry. A volume in micro and nano technologies. Elsevier; 2019. pp. 567-593. https://doi.org/10.1016/B978-0-12-815886-9.00023-1 Piñón-Segundo E, Mendoza-Muñoz N, Quintanar-Guerrero D. Nanoparticles as dental drug-delivery systems. In: Subramani K, Ahmed W, editors. Nanobiomaterials in clinical dentistry. A volume in micro and nano technologies. Elsevier; 2019. pp. 567-593. https://doi.org/10.1016/B978-0-12-815886-9.00023-1 Qin Y, Liu Y, Yuan L, Yong H, Liu J. Preparation and characterization of antioxidant, antimicrobial and pH-sensitive films based on chitosan, silver nanoparticles and purple corn extract. Food Hydrocolloids. 2019;96:102-111. https://doi.org/10.1016/j.foodhyd.2019.05.017 Qin Y, Liu Y, Yuan L, Yong H, Liu J. Preparation and characterization of antioxidant, antimicrobial and pH-sensitive films based on chitosan, silver nanoparticles and purple corn extract. Food Hydrocolloids. 2019;96:102-111. https://doi.org/10.1016/j.foodhyd.2019.05.017 Sun J, Jiangm H, Wu H, Tong C, Pang J, Wu C. Multifunctional bionanocomposite films based on konjac glucomannan/chitosan with nano-ZnO and mulberry anthocyanin extract for active food packaging. Food Hydrocolloids. 2020;107. https://doi.org/10.1016/j.foodhyd.2020.105942 Sun J, Jiangm H, Wu H, Tong C, Pang J, Wu C. Multifunctional bionanocomposite films based on konjac glucomannan/chitosan with nano-ZnO and mulberry anthocyanin extract for active food packaging. Food Hydrocolloids. 2020;107. https://doi.org/10.1016/j.foodhyd.2020.105942 Gmoshinski IV, Ananyan MA, Shipelin VA, Riger NA, Trushina EN, Mustafina OK, et al. Effect of dihydroquercetin on the toxic properties of nickel nanoparticles. Foods and Raw Materials. 2023;11(2):232-242. https://doi.org/10.21603/2308-4057-2023-2-572 Gmoshinski IV, Ananyan MA, Shipelin VA, Riger NA, Trushina EN, Mustafina OK, et al. Effect of dihydroquercetin on the toxic properties of nickel nanoparticles. Foods and Raw Materials. 2023;11(2):232-242. https://doi.org/10.21603/2308-4057-2023-2-572 Khan SA, Noreen F, Kanwal S, Iqbal A, Hussain G. Green synthesis of ZnO and Cu-doped ZnO nanoparticles from leaf extracts of Abutilon indicum, Clerodendrum infortunatum, Clerodendrum inerme and investigation of their biological and photocatalytic activities. Materials Science and Engineering: C. 2018;82:46-59. https://doi.org/10.1016/j.msec.2017.08.071 Khan SA, Noreen F, Kanwal S, Iqbal A, Hussain G. Green synthesis of ZnO and Cu-doped ZnO nanoparticles from leaf extracts of Abutilon indicum, Clerodendrum infortunatum, Clerodendrum inerme and investigation of their biological and photocatalytic activities. Materials Science and Engineering: C. 2018;82:46-59. https://doi.org/10.1016/j.msec.2017.08.071 Rai M, Yadav A, Gad A. Silver nanoparticles as a new generation of antimicrobials. Biotechnology Advances. 2009;27(1):76-83. https://doi.org/10.1016/j.biotechadv.2008.09.002 Rai M, Yadav A, Gad A. Silver nanoparticles as a new generation of antimicrobials. Biotechnology Advances. 2009;27(1):76-83. https://doi.org/10.1016/j.biotechadv.2008.09.002 Marambio-Jones C, Hoek EMV. A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment. Journal of Nanoparticle Research. 2010;12:1531-1551. https://doi.org/10.1007/s11051-010-9900-y Marambio-Jones C, Hoek EMV. A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment. Journal of Nanoparticle Research. 2010;12:1531-1551. https://doi.org/10.1007/s11051-010-9900-y Cui Y, Zhao Y, Tian Y, Zhang W, Lü X, Jiang X. The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli. Biomaterials. 2012;33(7):2327-2333. https://doi.org/10.1016/j.biomaterials.2011.11.057 Cui Y, Zhao Y, Tian Y, Zhang W, Lü X, Jiang X. The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli. Biomaterials. 2012;33(7):2327-2333. https://doi.org/10.1016/j.biomaterials.2011.11.057 Dhayalan M, Denison MIJ, Ayyar M, Gandhi NN, Krishnan K, Abdulhadi B. Biogenic synthesis, characterization of gold and silver nanoparticles from Coleus forskohlii and their clinical importance. Journal of Photochemistry and Photobiology B: Biology. 2018;183:251-257. https://doi.org/10.1016/j.jphotobiol.2018.04.042 Dhayalan M, Denison MIJ, Ayyar M, Gandhi NN, Krishnan K, Abdulhadi B. Biogenic synthesis, characterization of gold and silver nanoparticles from Coleus forskohlii and their clinical importance. Journal of Photochemistry and Photobiology B: Biology. 2018;183:251-257. https://doi.org/10.1016/j.jphotobiol.2018.04.042 Kumar KP, Paul W, Sharma CP. Green synthesis of gold nanoparticles with Zingiber officinale extract: Characterization and blood compatibility. Process Biochemistry. 2011;46(10):2007-2013. https://doi.org/10.1016/j.procbio.2011.07.011 Kumar KP, Paul W, Sharma CP. Green synthesis of gold nanoparticles with Zingiber officinale extract: Characterization and blood compatibility. Process Biochemistry. 2011;46(10):2007-2013. https://doi.org/10.1016/j.procbio.2011.07.011 Vaseeharan B, Ramasamy P, Chen JC. Antibacterial activity of silver nanoparticles (AgNps) synthesized by tea leaf extracts against pathogenic Vibrio harveyi and its protective efficacy on juvenile Feneropenaeus indicus. Letters in Applied Microbiology. 2010;50(4):352-356. https://doi.org/10.1111/j.1472-765X.2010.02799.x Vaseeharan B, Ramasamy P, Chen JC. Antibacterial activity of silver nanoparticles (AgNps) synthesized by tea leaf extracts against pathogenic Vibrio harveyi and its protective efficacy on juvenile Feneropenaeus indicus. Letters in Applied Microbiology. 2010;50(4):352-356. https://doi.org/10.1111/j.1472-765X.2010.02799.x Gajbhiye M, Kesharwani J, Ingle A, Gade A, Rai M. Fungus-mediated synthesis of silver nanoparticles and their activity against pathogenic fungi in combination with fluconazole. Nanomedicine: Nanotechnology, Biology, and Medicine. 2009;5(4):382-386. https://doi.org/10.1016/j.nano.2009.06.005 Gajbhiye M, Kesharwani J, Ingle A, Gade A, Rai M. Fungus-mediated synthesis of silver nanoparticles and their activity against pathogenic fungi in combination with fluconazole. Nanomedicine: Nanotechnology, Biology, and Medicine. 2009;5(4):382-386. https://doi.org/10.1016/j.nano.2009.06.005 Tankhiwale R, Bajpai SK. Preparation, characterization and antibacterial applications of ZnO-nanoparticles coated polyethylene films for food packaging. Colloids and Surfaces B: Biointerfaces. 2012;90:16-20. https://doi.org/10.1016/j.colsurfb.2011.09.031 Tankhiwale R, Bajpai SK. Preparation, characterization and antibacterial applications of ZnO-nanoparticles coated polyethylene films for food packaging. Colloids and Surfaces B: Biointerfaces. 2012;90:16-20. https://doi.org/10.1016/j.colsurfb.2011.09.031 Bang Y-J, Shankar S, Rhim J-W. In situ synthesis of multi-functional gelatin/resorcinol/silver nanoparticles composite films. Food Packaging and Shelf Life. 2019;22. https://doi.org/10.1016/j.fpsl.2019.100399 Bang Y-J, Shankar S, Rhim J-W. In situ synthesis of multi-functional gelatin/resorcinol/silver nanoparticles composite films. Food Packaging and Shelf Life. 2019;22. https://doi.org/10.1016/j.fpsl.2019.100399 Liu J, Ma Z, Liu Y, Zheng X, Pei Y, Tang K. Soluble soybean polysaccharide films containing in-situ generated silver nanoparticles for antibacterial food packaging applications. Food Packaging and Shelf Life. 2022;31. https://doi.org/10.1016/j.fpsl.2021.100800 Liu J, Ma Z, Liu Y, Zheng X, Pei Y, Tang K. Soluble soybean polysaccharide films containing in-situ generated silver nanoparticles for antibacterial food packaging applications. Food Packaging and Shelf Life. 2022;31. https://doi.org/10.1016/j.fpsl.2021.100800 Perera KY, Jaiswal S, Jaiswal AK. A review on nanomaterials and nanohybrids based bio-nanocomposites for food packaging. Food Chemistry. 2022;376. https://doi.org/10.1016/j.foodchem.2021.131912 Perera KY, Jaiswal S, Jaiswal AK. A review on nanomaterials and nanohybrids based bio-nanocomposites for food packaging. Food Chemistry. 2022;376. https://doi.org/10.1016/j.foodchem.2021.131912 Khodashenas B, Ghorbani HR. Synthesis of silver nanoparticles with different shapes. Arabian Journal of Chemistry. 2019;12(8):1823-1838. https://doi.org/10.1016/j.arabjc.2014.12.014 Khodashenas B, Ghorbani HR. Synthesis of silver nanoparticles with different shapes. Arabian Journal of Chemistry. 2019;12(8):1823-1838. https://doi.org/10.1016/j.arabjc.2014.12.014 Dzulkharnien NSF, Rohani R. A review on current designation of metallic nanocomposite hydrogel in biomedical applications. Nanomaterials. 2022;12(10). https://doi.org/10.3390/nano12101629 Dzulkharnien NSF, Rohani R. A review on current designation of metallic nanocomposite hydrogel in biomedical applications. Nanomaterials. 2022;12(10). https://doi.org/10.3390/nano12101629 Rosli NA, Teow YH, Mahmoudi E. Current approaches for the exploration of antimicrobial activities of nanoparticles. Science and Technology of Advanced Materials. 2021;22(1):885-907. https://doi.org/10.1080/14686996.2021.1978801 Rosli NA, Teow YH, Mahmoudi E. Current approaches for the exploration of antimicrobial activities of nanoparticles. Science and Technology of Advanced Materials. 2021;22(1):885-907. https://doi.org/10.1080/14686996.2021.1978801 Shaikh S, Nazam N, Rizvi SMD, Ahmad K, Baig MH, Lee EJ, et al. Mechanistic insights into the antimicrobial actions of metallic nanoparticles and their implications for multidrug resistance. International Journal of Molecular Sciences. 2019;20(10). https://doi.org/10.3390/ijms20102468 Shaikh S, Nazam N, Rizvi SMD, Ahmad K, Baig MH, Lee EJ, et al. Mechanistic insights into the antimicrobial actions of metallic nanoparticles and their implications for multidrug resistance. International Journal of Molecular Sciences. 2019;20(10). https://doi.org/10.3390/ijms20102468 Beyth N, Houri-Haddad Y, Domb A, Khan W, Hazan R. Alternative antimicrobial approach: Nano-antimicrobial materials. Evidence-Based Complementary and Alternative Medicine. 2015;2015. https://doi.org/10.1155/2015/246012 Beyth N, Houri-Haddad Y, Domb A, Khan W, Hazan R. Alternative antimicrobial approach: Nano-antimicrobial materials. Evidence-Based Complementary and Alternative Medicine. 2015;2015. https://doi.org/10.1155/2015/246012 Jamkhande PG, Ghule NW, Bamer AH, Kalaskar MG. Metal nanoparticles synthesis: An overview on methods of preparation, advantages and disadvantages, and applications. Journal of Drug Delivery Science and Technology. 2019;53. https://doi.org/10.1016/j.jddst.2019.101174 Jamkhande PG, Ghule NW, Bamer AH, Kalaskar MG. Metal nanoparticles synthesis: An overview on methods of preparation, advantages and disadvantages, and applications. Journal of Drug Delivery Science and Technology. 2019;53. https://doi.org/10.1016/j.jddst.2019.101174 Balasooriya ER, Jayasinghe CD, Jayawardena UA, Ruwanthika RWD, de Silva RM, Udagama PV. Honey mediated green synthesis of nanoparticles: New era of safe nanotechnology. Journal of Nanomaterials. 2017;2017. https://doi.org/10.1155/2017/5919836 Balasooriya ER, Jayasinghe CD, Jayawardena UA, Ruwanthika RWD, de Silva RM, Udagama PV. Honey mediated green synthesis of nanoparticles: New era of safe nanotechnology. Journal of Nanomaterials. 2017;2017. https://doi.org/10.1155/2017/5919836 Lyu J, Xing S, Meng Y, Wu N, Yin C. Flexible superhydrophobic ZnO coating harvesting antibacterial and washable properties. Materials Letters. 2022;314. https://doi.org/10.1016/j.matlet.2022.131730 Lyu J, Xing S, Meng Y, Wu N, Yin C. Flexible superhydrophobic ZnO coating harvesting antibacterial and washable properties. Materials Letters. 2022;314. https://doi.org/10.1016/j.matlet.2022.131730 Hou Y, Mushtaq A, Tang Z, Dempsey E, Wu Y, Lu Y, et al. ROS-responsive Ag-TiO2 hybrid nanorods for enhanced photodynamic therapy of breast cancer and antimicrobial applications. Journal of Science: Advanced Materials and Devices. 2022;7(2). https://doi.org/10.1016/j.jsamd.2022.100417 Hou Y, Mushtaq A, Tang Z, Dempsey E, Wu Y, Lu Y, et al. ROS-responsive Ag-TiO2 hybrid nanorods for enhanced photodynamic therapy of breast cancer and antimicrobial applications. Journal of Science: Advanced Materials and Devices. 2022;7(2). https://doi.org/10.1016/j.jsamd.2022.100417 Maťátková O, Michailidu Ja, Miškovská A, Kolouchová I, Masák J, Čejková A. Antimicrobial properties and applications of metal nanoparticles biosynthesized by green methods. Biotechnology Advances. 2022;58. https://doi.org/10.1016/j.biotechadv.2022.107905 Maťátková O, Michailidu Ja, Miškovská A, Kolouchová I, Masák J, Čejková A. Antimicrobial properties and applications of metal nanoparticles biosynthesized by green methods. Biotechnology Advances. 2022;58. https://doi.org/10.1016/j.biotechadv.2022.107905 Chinnapaiyan M, Selvam Y, Bassyouni F, Ramu M, Sakkaraiveeranan C, Samickannian A, et al. Nanotechnology, green synthesis and biological activity application of zinc oxide nanoparticles incorporated argemone mxicana leaf extract. Molecules. 2022;27(5). https://doi.org/10.3390/molecules27051545 Chinnapaiyan M, Selvam Y, Bassyouni F, Ramu M, Sakkaraiveeranan C, Samickannian A, et al. Nanotechnology, green synthesis and biological activity application of zinc oxide nanoparticles incorporated argemone mxicana leaf extract. Molecules. 2022;27(5). https://doi.org/10.3390/molecules27051545 Dat TD, Viet ND, Dat NM, My PLT, Thinh DB, Thy LTM, et al. Characterization and bioactivities of silver nanoparticles green synthesized from Vietnamese Ganoderma lucidum. Surfaces and Interfaces. 2021;27. https://doi.org/10.1016/j.surfin.2021.101453 Dat TD, Viet ND, Dat NM, My PLT, Thinh DB, Thy LTM, et al. Characterization and bioactivities of silver nanoparticles green synthesized from Vietnamese Ganoderma lucidum. Surfaces and Interfaces. 2021;27. https://doi.org/10.1016/j.surfin.2021.101453 Singh P, Garg A, Pandit S, Mokkapati VRSS, Mijakovic I. Antimicrobial effects of biogenic nanoparticles. Nanomaterials. 2018;8(12). https://doi.org/10.3390/nano8121009 Singh P, Garg A, Pandit S, Mokkapati VRSS, Mijakovic I. Antimicrobial effects of biogenic nanoparticles. Nanomaterials. 2018;8(12). https://doi.org/10.3390/nano8121009 Liu Z, Persson S, Sánchez-Rodríguez C. At the border: the plasma membrane-cell wall continuum. Journal of Experimental Botany. 2015;66(6):1553-1563. https://doi.org/10.1093/jxb/erv019 Liu Z, Persson S, Sánchez-Rodríguez C. At the border: the plasma membrane-cell wall continuum. Journal of Experimental Botany. 2015;66(6):1553-1563. https://doi.org/10.1093/jxb/erv019 Swaminathan M, Sharma NK. Antimicrobial activity of the engineered nanoparticles used as coating agents. In: Martínez LMT, Kharissova OV, Kharisov BI, editors. Handbook of ecomaterials. Cham: Springer; 2017. pp. 1-15. https://doi.org/10.1007/978-3-319-48281-1_1-1 Swaminathan M, Sharma NK. Antimicrobial activity of the engineered nanoparticles used as coating agents. In: Martínez LMT, Kharissova OV, Kharisov BI, editors. Handbook of ecomaterials. Cham: Springer; 2017. pp. 1-15. https://doi.org/10.1007/978-3-319-48281-1_1-1 Dong Y, Zhu H, Shen Y, Zhang W, Zhang L. Antibacterial activity of silver nanoparticles of different particle size against Vibrio natriegens. PLoS ONE. 2019;14(9). https://doi.org/10.1371/journal.pone.0222322 Dong Y, Zhu H, Shen Y, Zhang W, Zhang L. Antibacterial activity of silver nanoparticles of different particle size against Vibrio natriegens. PLoS ONE. 2019;14(9). https://doi.org/10.1371/journal.pone.0222322 Flores-López LZ, Espinoza-Gómez H, Somanathan R. Silver nanoparticles: Electron transfer, reactive oxygen species, oxidative stress, beneficial and toxicological effects. Mini review. Journal of Applied Toxicology. 2018;39(1):16-26. https://doi.org/10.1002/jat.3654 Flores-López LZ, Espinoza-Gómez H, Somanathan R. Silver nanoparticles: Electron transfer, reactive oxygen species, oxidative stress, beneficial and toxicological effects. Mini review. Journal of Applied Toxicology. 2018;39(1):16-26. https://doi.org/10.1002/jat.3654 Dai Y, Wang Z, Zhao J, Xu L, Xu L, Yu X, et al. Interaction of CuO nanoparticles with plant cells: internalization, oxidative stress, electron transport chain disruption, and toxicogenomic responses. Environmental Science: Nano. 2018;5(10):2269-2281. https://doi.org/10.1039/C8EN00222C Dai Y, Wang Z, Zhao J, Xu L, Xu L, Yu X, et al. Interaction of CuO nanoparticles with plant cells: internalization, oxidative stress, electron transport chain disruption, and toxicogenomic responses. Environmental Science: Nano. 2018;5(10):2269-2281. https://doi.org/10.1039/C8EN00222C Muntean DM, Sturza A, Dănilă MD, Borza C, Duicu OM, Mornoș C. The role of mitochondrial reactive oxygen species in cardiovascular injury and protective strategies. Oxidative Medicine and Cellular Longevity. 2016;2016. http://doi.org/10.1155/2016/8254942 Muntean DM, Sturza A, Dănilă MD, Borza C, Duicu OM, Mornoș C. The role of mitochondrial reactive oxygen species in cardiovascular injury and protective strategies. Oxidative Medicine and Cellular Longevity. 2016;2016. http://doi.org/10.1155/2016/8254942 Liu J, Peng Q. Protein-gold nanoparticle interactions and their possible impact on biomedical applications. Acta Biomaterialia. 2017;55:13-27. https://doi.org/10.1016/j.actbio.2017.03.055 Liu J, Peng Q. Protein-gold nanoparticle interactions and their possible impact on biomedical applications. Acta Biomaterialia. 2017;55:13-27. https://doi.org/10.1016/j.actbio.2017.03.055 Wang LL, Hu C, Shao LQ. The antimicrobial activity of nanoparticles: present situation and prospects for the future. International Journal of Nanomedicine. 2017;12:1227-1249. https://doi.org/10.2147/IJN.S121956 Wang LL, Hu C, Shao LQ. The antimicrobial activity of nanoparticles: present situation and prospects for the future. International Journal of Nanomedicine. 2017;12:1227-1249. https://doi.org/10.2147/IJN.S121956 Kaur P, Nene AG, Sharma D, Somani PR, Tuli HS. Synergistic effect of copper nanoparticles and antibiotics to enhance antibacterial potential. Bio-Materials and Technology. 2019;1(1):33-47. Kaur P, Nene AG, Sharma D, Somani PR, Tuli HS. Synergistic effect of copper nanoparticles and antibiotics to enhance antibacterial potential. Bio-Materials and Technology. 2019;1(1):33-47. Oliani WL, Pusceddu FH, Parra DF. Silver-titanium polymeric nanocomposite non ecotoxic with bactericide activity. Polymer Bulletin. 2022;79:10949-10968. https://doi.org/10.1007/s00289-021-04036-7 Oliani WL, Pusceddu FH, Parra DF. Silver-titanium polymeric nanocomposite non ecotoxic with bactericide activity. Polymer Bulletin. 2022;79:10949-10968. https://doi.org/10.1007/s00289-021-04036-7 Zhang M, Zheng Y, Jin Y, Wang D, Wang G, Zhang X, et al. Ag@MOF-loaded p-coumaric acid modified chitosan/chitosan nanoparticle and polyvinyl alcohol/starch bilayer films for food packing applications. International Journal of Biological Macromolecules. 2022;202:80-90. https://doi.org/10.1016/j.ijbiomac.2022.01.074 Zhang M, Zheng Y, Jin Y, Wang D, Wang G, Zhang X, et al. Ag@MOF-loaded p-coumaric acid modified chitosan/chitosan nanoparticle and polyvinyl alcohol/starch bilayer films for food packing applications. International Journal of Biological Macromolecules. 2022;202:80-90. https://doi.org/10.1016/j.ijbiomac.2022.01.074 Haddar A, Ayed EB, Sila A, Putaux J-L, Bougatef A, Boufic S. Hybrid levan-Ag/AgCl nanoparticles produced by UV-irradiation: Properties, antibacterial efficiency and application in bioactive poly(vinyl alcohol) films. RSC Advance. 2021;11:38990-39003. https://doi.org/10.1039/D1RA07852F Haddar A, Ayed EB, Sila A, Putaux J-L, Bougatef A, Boufic S. Hybrid levan-Ag/AgCl nanoparticles produced by UV-irradiation: Properties, antibacterial efficiency and application in bioactive poly(vinyl alcohol) films. RSC Advance. 2021;11:38990-39003. https://doi.org/10.1039/D1RA07852F Gasti T, Hiremani VD, Kesti ShS, Vanjeri VN, Goudar N, Masti SP, et al. Physicochemical and antibacterial evaluation of poly (vinyl alcohol)/guar gum/silver nanocomposite films for food packaging applications. Journal of Polymers and the Environment. 2021;29:3347-3363. https://doi.org/10.1007/s10924-021-02123-4 Gasti T, Hiremani VD, Kesti ShS, Vanjeri VN, Goudar N, Masti SP, et al. Physicochemical and antibacterial evaluation of poly (vinyl alcohol)/guar gum/silver nanocomposite films for food packaging applications. Journal of Polymers and the Environment. 2021;29:3347-3363. https://doi.org/10.1007/s10924-021-02123-4 Adel AM, Al-Shemy MT, Diab MA, El-Sakhawy M, Toro RG, Montanari R, et al. Fabrication of packaging paper sheets decorated with alginate/oxidized nanocellulose-silver nanoparticles bio-nanocomposite. International Journal of Biological Macromolecules. 2021;181:612-620. https://doi.org/10.1016/j.ijbiomac.2021.03.182 Adel AM, Al-Shemy MT, Diab MA, El-Sakhawy M, Toro RG, Montanari R, et al. Fabrication of packaging paper sheets decorated with alginate/oxidized nanocellulose-silver nanoparticles bio-nanocomposite. International Journal of Biological Macromolecules. 2021;181:612-620. https://doi.org/10.1016/j.ijbiomac.2021.03.182 Gu B, Jiang Q, Luo B, Liu C, Ren J, Wang X, et al. A sandwich-like chitosan-based antibacterial nanocomposite film with reduced graphene oxide immobilized silver nanoparticles. Carbohydrate Polymers. 2021;260. https://doi.org/10.1016/j.carbpol.2021.117835 Gu B, Jiang Q, Luo B, Liu C, Ren J, Wang X, et al. A sandwich-like chitosan-based antibacterial nanocomposite film with reduced graphene oxide immobilized silver nanoparticles. Carbohydrate Polymers. 2021;260. https://doi.org/10.1016/j.carbpol.2021.117835 Khurshid S, Arif S, Ali TM, Iqbal HM, Shaikh M, Khurshid H, et al. Effect of silver nanoparticles prepared from Saraca asoca leaf extract on morphological, functional, mechanical, and antibacterial properties of rice starch films. Starch - Stärke. 2022;74(5-6). https://doi.org/10.1002/star.202100228 Khurshid S, Arif S, Ali TM, Iqbal HM, Shaikh M, Khurshid H, et al. Effect of silver nanoparticles prepared from Saraca asoca leaf extract on morphological, functional, mechanical, and antibacterial properties of rice starch films. Starch - Stärke. 2022;74(5-6). https://doi.org/10.1002/star.202100228 Ardjoum N, Shankar S, Chibani N, Salmieri S, Lacroix M. In situ synthesis of silver nanoparticles in pectin matrix using gamma irradiation for the preparation of antibacterial pectin/silver nanoparticles composite films. Food Hydrocolloids. 2021;121. https://doi.org/10.1016/j.foodhyd.2021.107000 Ardjoum N, Shankar S, Chibani N, Salmieri S, Lacroix M. In situ synthesis of silver nanoparticles in pectin matrix using gamma irradiation for the preparation of antibacterial pectin/silver nanoparticles composite films. Food Hydrocolloids. 2021;121. https://doi.org/10.1016/j.foodhyd.2021.107000 Dash KK, Kumar A, Kumari S, Malik MA. Silver nanoparticle incorporated flaxseed protein-alginate composite films: Effect on physicochemical, mechanical, and thermal properties. Journal of Polymers and the Environment. 2021;29:3649-3659. https://doi.org/10.1007/s10924-021-02137-y Dash KK, Kumar A, Kumari S, Malik MA. Silver nanoparticle incorporated flaxseed protein-alginate composite films: Effect on physicochemical, mechanical, and thermal properties. Journal of Polymers and the Environment. 2021;29:3649-3659. https://doi.org/10.1007/s10924-021-02137-y Wang L, Periyasami G, Aldalbahi A, Fogliano V. The antimicrobial activity of silver nanoparticles biocomposite films depends on the silver ions release behaviour. Food Chemistry. 2021;359. https://doi.org/10.1016/j.foodchem.2021.129859 Wang L, Periyasami G, Aldalbahi A, Fogliano V. The antimicrobial activity of silver nanoparticles biocomposite films depends on the silver ions release behaviour. Food Chemistry. 2021;359. https://doi.org/10.1016/j.foodchem.2021.129859 Sallak N, Moghanjoughi AM, Ataee M, Anvar A, Golestan L. Antimicrobial biodegradable film based on corn starch/Satureja khuzestanica essential oil/Ag-TiO2 nanocomposites. Nanotechnology. 2021;32(40). https://doi.org/10.1088/1361-6528/ac0a15 Sallak N, Moghanjoughi AM, Ataee M, Anvar A, Golestan L. Antimicrobial biodegradable film based on corn starch/Satureja khuzestanica essential oil/Ag-TiO2 nanocomposites. Nanotechnology. 2021;32(40). https://doi.org/10.1088/1361-6528/ac0a15 Mintiwab A, Jeyaramraja PR. Evaluation of phytochemical components, antioxidant and antibacterial activities of silver nanoparticles synthesized using Ricinus communis leaf extracts. Vegetos. 2021;34:606-618. https://doi.org/10.1007/s42535-021-00244-8 Mintiwab A, Jeyaramraja PR. Evaluation of phytochemical components, antioxidant and antibacterial activities of silver nanoparticles synthesized using Ricinus communis leaf extracts. Vegetos. 2021;34:606-618. https://doi.org/10.1007/s42535-021-00244-8 Burmistrov DE, Simakin AV, Smirnova VV, Uvarov OV, Ivashkin PI, Kucherov RN, et al. Bacteriostatic and cytotoxic properties of composite material based on ZnO nanoparticles in PLGA obtained by low temperature method. Polymers. 2022;14(1). https://doi.org/10.3390/polym14010049 Burmistrov DE, Simakin AV, Smirnova VV, Uvarov OV, Ivashkin PI, Kucherov RN, et al. Bacteriostatic and cytotoxic properties of composite material based on ZnO nanoparticles in PLGA obtained by low temperature method. Polymers. 2022;14(1). https://doi.org/10.3390/polym14010049 Ching LW, Keesan FWM, Muhamad II. Optimization of ZnO/GO nanocomposite-loaded polylactic acid active films using response surface methodology. Journal of King Saud University - Science. 2022;34(3). https://doi.org/10.1016/j.jksus.2022.101835 Ching LW, Keesan FWM, Muhamad II. Optimization of ZnO/GO nanocomposite-loaded polylactic acid active films using response surface methodology. Journal of King Saud University - Science. 2022;34(3). https://doi.org/10.1016/j.jksus.2022.101835 Saedi S, Shokri M, Priyadarshi R, Rhim J-Wh. Carrageenan-based antimicrobial films integrated with sulfur-coated iron oxide nanoparticles (Fe3O4@SNP). ACS Applied Polymer Materials. 2021;3(10):4913-4923. https://doi.org/10.1021/acsapm.1c00690 Saedi S, Shokri M, Priyadarshi R, Rhim J-Wh. Carrageenan-based antimicrobial films integrated with sulfur-coated iron oxide nanoparticles (Fe3O4@SNP). ACS Applied Polymer Materials. 2021;3(10):4913-4923. https://doi.org/10.1021/acsapm.1c00690 Tymczewska A, Furtado BU, Nowaczyk J, Hrynkiewicz K, Szydłowska-Czerniak A. Functional properties of gelatin/polyvinyl alcohol films containing black cumin cake extract and zinc oxide nanoparticles produced via casting technique. International Journal of Molecular Sciences. 2022;23(5). https://doi.org/10.3390/ijms23052734 Tymczewska A, Furtado BU, Nowaczyk J, Hrynkiewicz K, Szydłowska-Czerniak A. Functional properties of gelatin/polyvinyl alcohol films containing black cumin cake extract and zinc oxide nanoparticles produced via casting technique. International Journal of Molecular Sciences. 2022;23(5). https://doi.org/10.3390/ijms23052734 Abolhassani S, Alipour H, Alizadeh A, Nemati MM, Najafi H, Alavi O. Antibacterial effect of electrospun polyurethane-gelatin loaded with honey and ZnO nanoparticles as potential wound dressing. Journal of Industrial Textiles. 2022;5(1S):954S-968S. https://doi.org/10.1177/15280837211069871 Abolhassani S, Alipour H, Alizadeh A, Nemati MM, Najafi H, Alavi O. Antibacterial effect of electrospun polyurethane-gelatin loaded with honey and ZnO nanoparticles as potential wound dressing. Journal of Industrial Textiles. 2022;5(1S):954S-968S. https://doi.org/10.1177/15280837211069871 Khalid H, Iqbal H, Zeeshan R, Nasir M, Sharif F, Akram M, et al. Silk fibroin/collagen 3D scaffolds loaded with TiO2 nanoparticles for skin tissue regeneration. Polymer Bulletin. 2021;78:7199-7218. https://doi.org/10.1007/s00289-020-03475-y Khalid H, Iqbal H, Zeeshan R, Nasir M, Sharif F, Akram M, et al. Silk fibroin/collagen 3D scaffolds loaded with TiO2 nanoparticles for skin tissue regeneration. Polymer Bulletin. 2021;78:7199-7218. https://doi.org/10.1007/s00289-020-03475-y Huang X, Zhou X, Dai Q, Qin Z. Antibacterial, antioxidation, uv-blocking, and biodegradable soy protein isolate food packaging film with mangosteen peel extract and ZnO nanoparticles. Nanomaterials. 2021;11(12). https://doi.org/10.3390/nano11123337 Huang X, Zhou X, Dai Q, Qin Z. Antibacterial, antioxidation, uv-blocking, and biodegradable soy protein isolate food packaging film with mangosteen peel extract and ZnO nanoparticles. Nanomaterials. 2021;11(12). https://doi.org/10.3390/nano11123337 Roy S, Rhim J-W. Preparation of pectin/agar-based functional films integrated with zinc sulfide nano petals for active packaging applications. Colloids and Surfaces B: Biointerfaces. 2021;207. https://doi.org/10.1016/j.colsurfb.2021.111999 Roy S, Rhim J-W. Preparation of pectin/agar-based functional films integrated with zinc sulfide nano petals for active packaging applications. Colloids and Surfaces B: Biointerfaces. 2021;207. https://doi.org/10.1016/j.colsurfb.2021.111999 Lee SW, Said NS, Sarbon NM. The effects of zinc oxide nanoparticles on the physical, mechanical and antimicrobial properties of chicken skin gelatin/tapioca starch composite films in food packaging. Journal of Food Science and Technology. 2021;58(11):4294-4302. https://doi.org/10.1007/s13197-020-04904-6 Lee SW, Said NS, Sarbon NM. The effects of zinc oxide nanoparticles on the physical, mechanical and antimicrobial properties of chicken skin gelatin/tapioca starch composite films in food packaging. Journal of Food Science and Technology. 2021;58(11):4294-4302. https://doi.org/10.1007/s13197-020-04904-6 Ding J, Hui A, Wang W, Yang F, Kang Y, Wang A. Multifunctional palygorskite@ZnO nanorods enhance simultaneously mechanical strength and antibacterial properties of chitosan-based film. International Journal of Biological Macromolecules. 2021;189:668-677. https://doi.org/10.1016/j.ijbiomac.2021.08.107 Ding J, Hui A, Wang W, Yang F, Kang Y, Wang A. Multifunctional palygorskite@ZnO nanorods enhance simultaneously mechanical strength and antibacterial properties of chitosan-based film. International Journal of Biological Macromolecules. 2021;189:668-677. https://doi.org/10.1016/j.ijbiomac.2021.08.107 Ahmad AA, Sarbon NM. A comparative study: Physical, mechanical and antibacterial properties of bio-composite gelatin films as influenced by chitosan and zinc oxide nanoparticles incorporation. Food Bioscience. 2021;43. https://doi.org/10.1016/j.fbio.2021.101250 Ahmad AA, Sarbon NM. A comparative study: Physical, mechanical and antibacterial properties of bio-composite gelatin films as influenced by chitosan and zinc oxide nanoparticles incorporation. Food Bioscience. 2021;43. https://doi.org/10.1016/j.fbio.2021.101250 Hasanzadeh Y, Hamidinezhad H, Ashkarran AA. Shape dependent antibacterial activity of various forms of ZnO nanostructures. BioNanoScience. 2021;11:893-900. https://doi.org/10.1007/s12668-021-00870-1 Hasanzadeh Y, Hamidinezhad H, Ashkarran AA. Shape dependent antibacterial activity of various forms of ZnO nanostructures. BioNanoScience. 2021;11:893-900. https://doi.org/10.1007/s12668-021-00870-1 Appu M, Lian Z, Zhao D, Huang J. Biosynthesis of chitosan-coated iron oxide (Fe3O4) hybrid nanocomposites from leaf extracts of Brassica oleracea L. and study on their antibacterial potentials. 3 Biotech. 2021;11. https://doi.org/10.1007/s13205-021-02820-w Appu M, Lian Z, Zhao D, Huang J. Biosynthesis of chitosan-coated iron oxide (Fe3O4) hybrid nanocomposites from leaf extracts of Brassica oleracea L. and study on their antibacterial potentials. 3 Biotech. 2021;11. https://doi.org/10.1007/s13205-021-02820-w Yaseen MW, Sufyan M, Nazir R, Naseem A, Shah R, Sheikh AA, et al. Simple and cost-effective approach to synthesis of iron magnesium oxide nanoparticles using Alstonia scholaris and Polyalthia longifolia leaves extracts and their antimicrobial, antioxidant and larvicidal activities. Applied Nanoscience. 2021;11:2479-2488. https://doi.org/10.1007/s13204-021-02051-8 Yaseen MW, Sufyan M, Nazir R, Naseem A, Shah R, Sheikh AA, et al. Simple and cost-effective approach to synthesis of iron magnesium oxide nanoparticles using Alstonia scholaris and Polyalthia longifolia leaves extracts and their antimicrobial, antioxidant and larvicidal activities. Applied Nanoscience. 2021;11:2479-2488. https://doi.org/10.1007/s13204-021-02051-8 Ramji V, Vishnuvarthanan M. Influence of NiO supported silica nanoparticles on mechanical, barrier, optical and antibacterial properties of polylactic acid (PLA) bio nanocomposite films for food packaging applications. Silicon. 2022;14:531-538. https://doi.org/10.1007/s12633-020-00839-x Ramji V, Vishnuvarthanan M. Influence of NiO supported silica nanoparticles on mechanical, barrier, optical and antibacterial properties of polylactic acid (PLA) bio nanocomposite films for food packaging applications. Silicon. 2022;14:531-538. https://doi.org/10.1007/s12633-020-00839-x Marand SA, Almasi H, Marand NA. Chitosan-based nanocomposite films incorporated with NiO nanoparticles: Physicochemical, photocatalytic and antimicrobial properties. International Journal of Biological Macromolecules. 2021;190:667-678. https://doi.org/10.1016/j.ijbiomac.2021.09.024 Marand SA, Almasi H, Marand NA. Chitosan-based nanocomposite films incorporated with NiO nanoparticles: Physicochemical, photocatalytic and antimicrobial properties. International Journal of Biological Macromolecules. 2021;190:667-678. https://doi.org/10.1016/j.ijbiomac.2021.09.024 Al-Tayyar NA, Youssef AM, Al-hindi R. Antimicrobial food packaging based on sustainable Bio-based materials for reducing foodborne Pathogens: A review. Food Chemistry. 2020;310. https://doi.org/10.1016/j.foodchem.2019.125915 Al-Tayyar NA, Youssef AM, Al-hindi R. Antimicrobial food packaging based on sustainable Bio-based materials for reducing foodborne Pathogens: A review. Food Chemistry. 2020;310. https://doi.org/10.1016/j.foodchem.2019.125915 Ezati P, Riahi Z, Rhim J-W. CMC-based functional film incorporated with copper-doped TiO2 to prevent banana browning. Food Hydrocolloids. 2022;122. https://doi.org/10.1016/j.foodhyd.2021.107104 Ezati P, Riahi Z, Rhim J-W. CMC-based functional film incorporated with copper-doped TiO2 to prevent banana browning. Food Hydrocolloids. 2022;122. https://doi.org/10.1016/j.foodhyd.2021.107104 Helmiyati H, Hidayat ZSZ, Sitanggang IFR, Liftyawati D. Antimicrobial packaging of ZnO-Nps infused into CMC-PVA nanocomposite films effectively enhances the physicochemical properties. Polymer Testing. 2021;104. https://doi.org/10.1016/j.polymertesting.2021.107412 Helmiyati H, Hidayat ZSZ, Sitanggang IFR, Liftyawati D. Antimicrobial packaging of ZnO-Nps infused into CMC-PVA nanocomposite films effectively enhances the physicochemical properties. Polymer Testing. 2021;104. https://doi.org/10.1016/j.polymertesting.2021.107412 Liu J, Huang J, Hu Z, Li G, Hu L, Chen X, et al. Chitosan-based films with antioxidant of bamboo leaves and ZnO nanoparticles for application in active food packaging. International Journal of Biological Macromolecules. 2021;189:363-369. https://doi.org/10.1016/j.ijbiomac.2021.08.136 Liu J, Huang J, Hu Z, Li G, Hu L, Chen X, et al. Chitosan-based films with antioxidant of bamboo leaves and ZnO nanoparticles for application in active food packaging. International Journal of Biological Macromolecules. 2021;189:363-369. https://doi.org/10.1016/j.ijbiomac.2021.08.136 Yu F, Fei X, He Y, Li H. Poly(lactic acid)-based composite film reinforced with acetylated cellulose nanocrystals and ZnO nanoparticles for active food packaging. International Journal of Biological Macromolecules. 2021;186:770-779. https://doi.org/10.1016/j.ijbiomac.2021.07.097 Yu F, Fei X, He Y, Li H. Poly(lactic acid)-based composite film reinforced with acetylated cellulose nanocrystals and ZnO nanoparticles for active food packaging. International Journal of Biological Macromolecules. 2021;186:770-779. https://doi.org/10.1016/j.ijbiomac.2021.07.097 Shahvalizadeh R, Ahmadi R, Davandeh I, Pezeshki A, Seyed Moslemi SA, Karimi S, et al. Antimicrobial bio-nanocomposite films based on gelatin, tragacanth, and zinc oxide nanoparticles - Microstructural, mechanical, thermo-physical, and barrier properties. Food Chemistry. 2021;354:129492. https://doi.org/10.1016/j.foodchem.2021.129492 Shahvalizadeh R, Ahmadi R, Davandeh I, Pezeshki A, Seyed Moslemi SA, Karimi S, et al. Antimicrobial bio-nanocomposite films based on gelatin, tragacanth, and zinc oxide nanoparticles - Microstructural, mechanical, thermo-physical, and barrier properties. Food Chemistry. 2021;354:129492. https://doi.org/10.1016/j.foodchem.2021.129492 Roy S, Rhim J-W. Gelatin-based film integrated with copper sulfide nanoparticles for active packaging applications. Applied Science. 2021;11(14). https://doi.org/10.3390/app11146307 Roy S, Rhim J-W. Gelatin-based film integrated with copper sulfide nanoparticles for active packaging applications. Applied Science. 2021;11(14). https://doi.org/10.3390/app11146307 Li X, Ren Z, Wang R, Liu L, Zhang J, Ma F, et al. Characterization and antibacterial activity of edible films based on carboxymethyl cellulose, Dioscorea opposita mucilage, glycerol and ZnO nanoparticles. Food Chemistry. 2021;349. https://doi.org/10.1016/j.foodchem.2021.129208 Li X, Ren Z, Wang R, Liu L, Zhang J, Ma F, et al. Characterization and antibacterial activity of edible films based on carboxymethyl cellulose, Dioscorea opposita mucilage, glycerol and ZnO nanoparticles. Food Chemistry. 2021;349. https://doi.org/10.1016/j.foodchem.2021.129208 Lian R, Cao J, Jiang X, Rogachev AV. Physicochemical, antibacterial properties and cytocompatibility of starch/chitosan films incorporated with zinc oxide nanoparticles. Materials Today Communications. 2021;27. https://doi.org/10.1016/j.mtcomm.2021.102265 Lian R, Cao J, Jiang X, Rogachev AV. Physicochemical, antibacterial properties and cytocompatibility of starch/chitosan films incorporated with zinc oxide nanoparticles. Materials Today Communications. 2021;27. https://doi.org/10.1016/j.mtcomm.2021.102265 Rathinavel S, Saravanakumar SS. Development and analysis of silver nano particle influenced PVA/natural particulate hybrid composites with thermo-mechanical properties. Journal of Polymers and the Environment. 2021;29:1894-1907. https://doi.org/10.1007/s10924-020-01999-y Rathinavel S, Saravanakumar SS. Development and analysis of silver nano particle influenced PVA/natural particulate hybrid composites with thermo-mechanical properties. Journal of Polymers and the Environment. 2021;29:1894-1907. https://doi.org/10.1007/s10924-020-01999-y Tymczewska A, Furtado BU, Nowaczyk J, Hrynkiewicz K, Szydłowska-Czerniak A. Functional properties of gelatin/polyvinyl alcohol films containing black cumin cake extract and zinc oxide nanoparticles produced via casting technique. International Journal of Molecular Sciences. 2022;23(5). https://doi.org/10.3390/ijms23052734 Tymczewska A, Furtado BU, Nowaczyk J, Hrynkiewicz K, Szydłowska-Czerniak A. Functional properties of gelatin/polyvinyl alcohol films containing black cumin cake extract and zinc oxide nanoparticles produced via casting technique. International Journal of Molecular Sciences. 2022;23(5). https://doi.org/10.3390/ijms23052734 Azari SSh, Alizadeh A, Roufegarinejad L, Asefi N, Hamishehkar H. Preparation and characterization of gelatin/β-glucan nanocomposite film incorporated with ZnO nanoparticles as an active food packaging system. Journal of Polymers and the Environment. 2021;29:1143-1152. https://doi.org/10.1007/s10924-020-01950-1 Azari SSh, Alizadeh A, Roufegarinejad L, Asefi N, Hamishehkar H. Preparation and characterization of gelatin/β-glucan nanocomposite film incorporated with ZnO nanoparticles as an active food packaging system. Journal of Polymers and the Environment. 2021;29:1143-1152. https://doi.org/10.1007/s10924-020-01950-1 Drago E, Campardelli R, Pettinato M, Perego P. Innovations in smart packaging concepts for food: An extensive review. Foods. 2020;9(11). https://doi.org/10.3390/foods9111628 Drago E, Campardelli R, Pettinato M, Perego P. Innovations in smart packaging concepts for food: An extensive review. Foods. 2020;9(11). https://doi.org/10.3390/foods9111628 Risch SJ. Food packaging history and innovations. Journal of Agricultural Food Chemistry. 2009;57(18):8089-8092. https://doi.org/10.1021/jf900040r Risch SJ. Food packaging history and innovations. Journal of Agricultural Food Chemistry. 2009;57(18):8089-8092. https://doi.org/10.1021/jf900040r Shaikh S, Yaqoob M, Aggarwal P. An overview of biodegradable packaging in food industry. Current Research in Food Science. 2021;4:503-520. https://doi.org/10.1016/j.crfs.2021.07.005 Shaikh S, Yaqoob M, Aggarwal P. An overview of biodegradable packaging in food industry. Current Research in Food Science. 2021;4:503-520. https://doi.org/10.1016/j.crfs.2021.07.005 Brizga J, Hubacek K, Feng K. The unintended side effects of bioplastics: Carbon, land, and water footprints. One Earth. 2020;3(4):515-516. https://doi.org/10.1016/j.oneear.2020.09.004 Brizga J, Hubacek K, Feng K. The unintended side effects of bioplastics: Carbon, land, and water footprints. One Earth. 2020;3(4):515-516. https://doi.org/10.1016/j.oneear.2020.09.004 Etxabide A, Uranga J, Guerrero P, de la Caba K. Development of active gelatin films by means of valorisation of food processing waste: A review. Food Hydrocolloids. 2017;68:192-198. https://doi.org/10.1016/j.foodhyd.2016.08.021 Etxabide A, Uranga J, Guerrero P, de la Caba K. Development of active gelatin films by means of valorisation of food processing waste: A review. Food Hydrocolloids. 2017;68:192-198. https://doi.org/10.1016/j.foodhyd.2016.08.021 Said NS, Howell NK, Sarbon NM. A review on potential use of gelatin-based film as active and smart biodegradable films for food packaging application. Food Reviews International. 2021;39(2):1063-1085. https://doi.org/10.1080/87559129.2021.1929298 Said NS, Howell NK, Sarbon NM. A review on potential use of gelatin-based film as active and smart biodegradable films for food packaging application. Food Reviews International. 2021;39(2):1063-1085. https://doi.org/10.1080/87559129.2021.1929298 Sohail M, Sun D-W, Zhu Z. Recent developments in intelligent packaging for enhancing food quality and safety. Critical Reviews in Food Science and Nutrition. 2018;58(15):2650-2662. https://doi.org/10.1080/10408398.2018.1449731 Sohail M, Sun D-W, Zhu Z. Recent developments in intelligent packaging for enhancing food quality and safety. Critical Reviews in Food Science and Nutrition. 2018;58(15):2650-2662. https://doi.org/10.1080/10408398.2018.1449731 Nogueira GF, Soares CT, Cavasini R, Fakhouri FM, de Oliveira RA. Bioactive films of arrowroot starch and blackberry pulp: Physical, mechanical and barrier properties and stability to pH and sterilization. Food Chemistry. 2019;275:417-425. https://doi.org/10.1016/j.foodchem.2018.09.054 Nogueira GF, Soares CT, Cavasini R, Fakhouri FM, de Oliveira RA. Bioactive films of arrowroot starch and blackberry pulp: Physical, mechanical and barrier properties and stability to pH and sterilization. Food Chemistry. 2019;275:417-425. https://doi.org/10.1016/j.foodchem.2018.09.054 Vanderroost M, Ragaert P, Devlieghere F, de Meulenaer B. Intelligent food packaging: The next generation. Trends in Food Science and Technology. 2014;39(1):47-62. https://doi.org/10.1016/j.tifs.2014.06.009 Vanderroost M, Ragaert P, Devlieghere F, de Meulenaer B. Intelligent food packaging: The next generation. Trends in Food Science and Technology. 2014;39(1):47-62. https://doi.org/10.1016/j.tifs.2014.06.009 Kerry JP, O’Grady MN, Hogan SA. Past, current and potential utilisation of active and intelligent packaging systems for meat and muscle-based products: A review. Meat Science. 2006;74(1):113-130. https://doi.org/10.1016/j.meatsci.2006.04.024 Kerry JP, O’Grady MN, Hogan SA. Past, current and potential utilisation of active and intelligent packaging systems for meat and muscle-based products: A review. Meat Science. 2006;74(1):113-130. https://doi.org/10.1016/j.meatsci.2006.04.024 Han J-W, Ruiz-Garcia L, Qian J-P, Yang X-T. Food packaging: A comprehensive review and future trends. Comprehensive Reviews in Food Science and Food Safety. 2018;17(4):860-877. https://doi.org/10.1111/1541-4337.12343 Han J-W, Ruiz-Garcia L, Qian J-P, Yang X-T. Food packaging: A comprehensive review and future trends. Comprehensive Reviews in Food Science and Food Safety. 2018;17(4):860-877. https://doi.org/10.1111/1541-4337.12343 Schaefera D, Cheung WM. Smart packaging: Opportunities and challenges. Procedia CIRP. 2018;72:1022-1027. https://doi.org/10.1016/j.procir.2018.03.240 Schaefera D, Cheung WM. Smart packaging: Opportunities and challenges. Procedia CIRP. 2018;72:1022-1027. https://doi.org/10.1016/j.procir.2018.03.240 Müller P, Schmid M. Intelligent packaging in the food sector: A brief overview. Foods. 2019;8(1). https://doi.org/10.3390/foods8010016 Müller P, Schmid M. Intelligent packaging in the food sector: A brief overview. Foods. 2019;8(1). https://doi.org/10.3390/foods8010016 Janjarasskul T, Suppakul P. Active and intelligent packaging: The indication of quality and safety. Critical Reviews in Food Science and Nutrition. 2018;58(5):808-831. https://doi.org/10.1080/10408398.2016.1225278 Janjarasskul T, Suppakul P. Active and intelligent packaging: The indication of quality and safety. Critical Reviews in Food Science and Nutrition. 2018;58(5):808-831. https://doi.org/10.1080/10408398.2016.1225278 Wicochea-Rodríguez JD, Chalier P, Ruiz T, Gastaldi E. Active food packaging based on biopolymers and aroma compounds: How to design and control the release. Frontiers in Chemistry. 2019;7. https://doi.org/10.3389/fchem.2019.00398 Wicochea-Rodríguez JD, Chalier P, Ruiz T, Gastaldi E. Active food packaging based on biopolymers and aroma compounds: How to design and control the release. Frontiers in Chemistry. 2019;7. https://doi.org/10.3389/fchem.2019.00398 Youssef AM, EL-Sayed SM, EL-Sayed HS, Salama HH, Dufresne A. Enhancement of Egyptian soft white cheese shelf life using a novel chitosan/carboxymethyl cellulose/zinc oxide bionanocomposite film. Carbohydrate Polymers. 2016;151:9-19. https://doi.org/10.1016/j.carbpol.2016.05.023 Youssef AM, EL-Sayed SM, EL-Sayed HS, Salama HH, Dufresne A. Enhancement of Egyptian soft white cheese shelf life using a novel chitosan/carboxymethyl cellulose/zinc oxide bionanocomposite film. Carbohydrate Polymers. 2016;151:9-19. https://doi.org/10.1016/j.carbpol.2016.05.023 Al-Nabulsi A, Osaili T, Sawalha A, Olaimat AN, Albiss BA, Mehyar G, et al. Antimicrobial activity of chitosan coating containing ZnO nanoparticles against E. coli O157:H7 on the surface of white brined cheese. International Journal of Food Microbiology. 2020;334. https://doi.org/10.1016/j.ijfoodmicro.2020.108838 Al-Nabulsi A, Osaili T, Sawalha A, Olaimat AN, Albiss BA, Mehyar G, et al. Antimicrobial activity of chitosan coating containing ZnO nanoparticles against E. coli O157:H7 on the surface of white brined cheese. International Journal of Food Microbiology. 2020;334. https://doi.org/10.1016/j.ijfoodmicro.2020.108838 Peter A, Cozmuta LM, Nicula C, Cozmuta AM, Talasman CM, Drazic G, et al. Chemical and organoleptic changes of curd cheese stored in new and reused active packaging systems made of Ag-graphene-TiO2-PLA. Food Chemistry. 2021;363. https://doi.org/10.1016/j.foodchem.2021.130341 Peter A, Cozmuta LM, Nicula C, Cozmuta AM, Talasman CM, Drazic G, et al. Chemical and organoleptic changes of curd cheese stored in new and reused active packaging systems made of Ag-graphene-TiO2-PLA. Food Chemistry. 2021;363. https://doi.org/10.1016/j.foodchem.2021.130341 Motelica L, Ficai D, Oprea O, Ficai A, Trusca R-D, Andronescu E, et al. Biodegradable alginate films with zno nanoparticles and citronella essential oil - A novel antimicrobial structure. Pharmaceutics. 2021;13(7). https://doi.org/10.3390/pharmaceutics13071020 Motelica L, Ficai D, Oprea O, Ficai A, Trusca R-D, Andronescu E, et al. Biodegradable alginate films with zno nanoparticles and citronella essential oil - A novel antimicrobial structure. Pharmaceutics. 2021;13(7). https://doi.org/10.3390/pharmaceutics13071020 Li W, Li L, Zhang H, Yuan M, Qin Y. Evaluation of PLA nanocomposite films on physicochemical and microbiological properties of refrigerated cottage cheese. Journal of Food Processing and Preservation. 2018;42(1). https://doi.org/10.1111/jfpp.13362 Li W, Li L, Zhang H, Yuan M, Qin Y. Evaluation of PLA nanocomposite films on physicochemical and microbiological properties of refrigerated cottage cheese. Journal of Food Processing and Preservation. 2018;42(1). https://doi.org/10.1111/jfpp.13362 Hosseinzadeh S, Partovi R, Talebi F, Babaei A. Chitosan/TiO2 nanoparticle/Cymbopogon citratus essential oil film as food packaging material: Physico-mechanical properties and its effects on microbial, chemical, and organoleptic quality of minced meat during refrigeration. Journal of Food Processing and Preservation. 2020;44(7). https://doi.org/10.1111/jfpp.14536 Hosseinzadeh S, Partovi R, Talebi F, Babaei A. Chitosan/TiO2 nanoparticle/Cymbopogon citratus essential oil film as food packaging material: Physico-mechanical properties and its effects on microbial, chemical, and organoleptic quality of minced meat during refrigeration. Journal of Food Processing and Preservation. 2020;44(7). https://doi.org/10.1111/jfpp.14536 Marcous A, Rasouli S, Ardestani F. Low-density polyethylene films loaded by titanium dioxide and zinc oxide nanoparticles as a new active packaging system against Escherichia coli O157:H7 in fresh calf minced meat. Packaging Technology and Science. 2017;30(11):693-701. https://doi.org/10.1002/pts.2312 Marcous A, Rasouli S, Ardestani F. Low-density polyethylene films loaded by titanium dioxide and zinc oxide nanoparticles as a new active packaging system against Escherichia coli O157:H7 in fresh calf minced meat. Packaging Technology and Science. 2017;30(11):693-701. https://doi.org/10.1002/pts.2312 Saedi S, Shokri M, Kim JT, Shin GH. Semi-transparent regenerated cellulose/ZnONP nanocomposite film as a potential antimicrobial food packaging material. Journal of Food Engineering. 2021;307. https://doi.org/10.1016/j.jfoodeng.2021.11066 Saedi S, Shokri M, Kim JT, Shin GH. Semi-transparent regenerated cellulose/ZnONP nanocomposite film as a potential antimicrobial food packaging material. Journal of Food Engineering. 2021;307. https://doi.org/10.1016/j.jfoodeng.2021.11066 Zhao X, Wang K, Ai C, Yan L, Jiang C, Shi J. Improvement of antifungal and antibacterial activities of food packages using silver nanoparticles synthesized by iturin A. Food Packaging and Shelf Life. 2021;28. https://doi.org/10.1016/j.fpsl.2021.100669 Zhao X, Wang K, Ai C, Yan L, Jiang C, Shi J. Improvement of antifungal and antibacterial activities of food packages using silver nanoparticles synthesized by iturin A. Food Packaging and Shelf Life. 2021;28. https://doi.org/10.1016/j.fpsl.2021.100669 Rasul NH, Asdagh A, Pirsa S, Ghazanfarirad N, Sani IK. Development of antimicrobial/antioxidant nanocomposite film based on fish skin gelatin and chickpea protein isolated containing Microencapsulated Nigella sativa essential oil and copper sulfide nanoparticles for extending minced meat shelf life. Materials Research Express. 2022;9. https://doi.org/10.1088/2053-1591/ac50d6 Rasul NH, Asdagh A, Pirsa S, Ghazanfarirad N, Sani IK. Development of antimicrobial/antioxidant nanocomposite film based on fish skin gelatin and chickpea protein isolated containing Microencapsulated Nigella sativa essential oil and copper sulfide nanoparticles for extending minced meat shelf life. Materials Research Express. 2022;9. https://doi.org/10.1088/2053-1591/ac50d6 Sayadi M, Langroodi AM, Amiri S, Radi M. Effect of nanocomposite alginate-based film incorporated with cumin essential oil and TiO2 nanoparticles on chemical, microbial, and sensory properties of fresh meat/beef. Food Science and Nutrition. 2022;10(5):1401-1413. https://doi.org/10.1002/fsn3.2724 Sayadi M, Langroodi AM, Amiri S, Radi M. Effect of nanocomposite alginate-based film incorporated with cumin essential oil and TiO2 nanoparticles on chemical, microbial, and sensory properties of fresh meat/beef. Food Science and Nutrition. 2022;10(5):1401-1413. https://doi.org/10.1002/fsn3.2724 Gasti T, Dixit S, Hiremani VD, Chougale RB, Masti SP, Vootla SK, et al. Chitosan/pullulan based films incorporated with clove essential oil loaded chitosan-ZnO hybrid nanoparticles for active food packaging. Carbohydrate Polymers. 2022;277. https://doi.org/10.1016/j.carbpol.2021.118866 Gasti T, Dixit S, Hiremani VD, Chougale RB, Masti SP, Vootla SK, et al. Chitosan/pullulan based films incorporated with clove essential oil loaded chitosan-ZnO hybrid nanoparticles for active food packaging. Carbohydrate Polymers. 2022;277. https://doi.org/10.1016/j.carbpol.2021.118866 Paidari S, Ahari H. The effects of nanosilver and nanoclay nanocomposites on shrimp (Penaeus semisulcatus) samples inoculated to food pathogens. Journal of Food Measurement and Characterization volume. 2021;15:3195-3206. https://doi.org/10.1007/s11694-021-00905-x Paidari S, Ahari H. The effects of nanosilver and nanoclay nanocomposites on shrimp (Penaeus semisulcatus) samples inoculated to food pathogens. Journal of Food Measurement and Characterization volume. 2021;15:3195-3206. https://doi.org/10.1007/s11694-021-00905-x Liu J, Huang J, Ying Y, Hu L, Hu Y. pH-sensitive and antibacterial films developed by incorporating anthocyanins extracted from purple potato or roselle into chitosan/polyvinyl alcohol/nano-ZnO matrix: Comparative study. International Journal of Biological Macromolecules. 2021;178:104-112. https://doi.org/10.1016/j.ijbiomac.2021.02.115 Liu J, Huang J, Ying Y, Hu L, Hu Y. pH-sensitive and antibacterial films developed by incorporating anthocyanins extracted from purple potato or roselle into chitosan/polyvinyl alcohol/nano-ZnO matrix: Comparative study. International Journal of Biological Macromolecules. 2021;178:104-112. https://doi.org/10.1016/j.ijbiomac.2021.02.115 Efatian H, Ahari H, Shahbazzadeh D, Nowruzi B, Yousefi S. Fabrication and characterization of LDPE/silver-copper/titanium dioxide nanocomposite films for application in Nile Tilapia (Oreochromis niloticus) packaging. Journal of Food Measurement and Characterization. 2021;15:2430-2439. https://doi.org/10.1007/s11694-021-00836-7 Efatian H, Ahari H, Shahbazzadeh D, Nowruzi B, Yousefi S. Fabrication and characterization of LDPE/silver-copper/titanium dioxide nanocomposite films for application in Nile Tilapia (Oreochromis niloticus) packaging. Journal of Food Measurement and Characterization. 2021;15:2430-2439. https://doi.org/10.1007/s11694-021-00836-7 Yinzhe R, Shaoying Z. Effect of carboxymethyl cellulose and alginate coating combined with brewer yeast on postharvest grape preservation. International Scholarly Research Notices. 2013;2013. https://doi.org/10.1155/2013/871396 Yinzhe R, Shaoying Z. Effect of carboxymethyl cellulose and alginate coating combined with brewer yeast on postharvest grape preservation. International Scholarly Research Notices. 2013;2013. https://doi.org/10.1155/2013/871396 Cheng J, Lin X, Wu X, Liu Q, Wan S, Zhang Y. Preparation of a multifunctional silver nanoparticles polylactic acid food packaging film using mango peel extract. International Journal of Biological Macromolecules. 2021;188:678-688. https://doi.org/10.1016/j.ijbiomac.2021.07.161 Cheng J, Lin X, Wu X, Liu Q, Wan S, Zhang Y. Preparation of a multifunctional silver nanoparticles polylactic acid food packaging film using mango peel extract. International Journal of Biological Macromolecules. 2021;188:678-688. https://doi.org/10.1016/j.ijbiomac.2021.07.161 Chaitanya Kumari S, Naga Padma P, Anuradha K. Green silver nanoparticles embedded in cellulosic network for fresh food packaging. Journal of Pure and Applied Microbiology. 2021;15(3):1236-1244. https://doi.org/10.22207/JPAM.15.3.13 Chaitanya Kumari S, Naga Padma P, Anuradha K. Green silver nanoparticles embedded in cellulosic network for fresh food packaging. Journal of Pure and Applied Microbiology. 2021;15(3):1236-1244. https://doi.org/10.22207/JPAM.15.3.13 Wang L, Tian Y, Zhang P, Li C, Chen J. Polysaccharide isolated from Rosa roxburghii Tratt fruit as a stabilizing and reducing agent for the synthesis of silver nanoparticles: antibacterial and preservative properties. Journal of Food Measurement and Characterization. 2022;16:1241-1251. https://doi.org/10.1007/s11694-021-01248-3 Wang L, Tian Y, Zhang P, Li C, Chen J. Polysaccharide isolated from Rosa roxburghii Tratt fruit as a stabilizing and reducing agent for the synthesis of silver nanoparticles: antibacterial and preservative properties. Journal of Food Measurement and Characterization. 2022;16:1241-1251. https://doi.org/10.1007/s11694-021-01248-3 Motlagh NV, Aghazamani J, Gholami R. Investigating the effect of nano-silver contained packaging on the olivier salad shelf-life. BioNanoScience. 2021;11:838-847. https://doi.org/10.1007/s12668-021-00876-9 Motlagh NV, Aghazamani J, Gholami R. Investigating the effect of nano-silver contained packaging on the olivier salad shelf-life. BioNanoScience. 2021;11:838-847. https://doi.org/10.1007/s12668-021-00876-9 Phothisarattana D, Wongphan P, Promhuad K, Promsorn J, Harnkarnsujarit N. Blown film extrusion of PBAT/TPS/ZnO nanocomposites for shelf-life extension of meat packaging. Colloids and Surfaces B: Biointerfaces. 2022;214. https://doi.org/10.1016/j.colsurfb.2022.112472 Phothisarattana D, Wongphan P, Promhuad K, Promsorn J, Harnkarnsujarit N. Blown film extrusion of PBAT/TPS/ZnO nanocomposites for shelf-life extension of meat packaging. Colloids and Surfaces B: Biointerfaces. 2022;214. https://doi.org/10.1016/j.colsurfb.2022.112472 Praseptiangga D, Widyaastuti D, Panatarani C, Joni IM. Development and characterization of semi-refined iota carrageenan/ SiO2-ZnO bionanocomposite film with the addition of cassava starch for application on minced chicken meat packaging. Foods. 2021;10(11). https://doi.org/10.3390/foods10112776 Praseptiangga D, Widyaastuti D, Panatarani C, Joni IM. Development and characterization of semi-refined iota carrageenan/ SiO2-ZnO bionanocomposite film with the addition of cassava starch for application on minced chicken meat packaging. Foods. 2021;10(11). https://doi.org/10.3390/foods10112776 Hong S-I, Cho Y, Rhim J-W. Effect of Agar/AgNP composite film packaging on refrigerated beef loin quality. Membranes. 2021;11(10). https://doi.org/10.3390/membranes11100750 Hong S-I, Cho Y, Rhim J-W. Effect of Agar/AgNP composite film packaging on refrigerated beef loin quality. Membranes. 2021;11(10). https://doi.org/10.3390/membranes11100750 Sani IK, Geshlaghi SP, Pirsa S, Asdagh A. Composite film based on potato starch/apple peel pectin/ZrO2 nanoparticles/ microencapsulated Zataria multiflora essential oil; investigation of physicochemical properties and use in quail meat packaging. Food Hydrocolloids. 2021;117. https://doi.org/10.1016/j.foodhyd.2021.106719 Sani IK, Geshlaghi SP, Pirsa S, Asdagh A. Composite film based on potato starch/apple peel pectin/ZrO2 nanoparticles/ microencapsulated Zataria multiflora essential oil; investigation of physicochemical properties and use in quail meat packaging. Food Hydrocolloids. 2021;117. https://doi.org/10.1016/j.foodhyd.2021.106719 Sani MA, Tavassoli M, Salim SA, Azizi-lalabadi M, McClements DJ. Development of green halochromic smart and active packaging materials: TiO2 nanoparticle- and anthocyanin-loaded gelatin/κ-carrageenan films. Food Hydrocolloids. 2022;124. https://doi.org/10.1016/j.foodhyd.2021.107324 Sani MA, Tavassoli M, Salim SA, Azizi-lalabadi M, McClements DJ. Development of green halochromic smart and active packaging materials: TiO2 nanoparticle- and anthocyanin-loaded gelatin/κ-carrageenan films. Food Hydrocolloids. 2022;124. https://doi.org/10.1016/j.foodhyd.2021.107324 Rizzotto F, Vasiljevic ZZ, Stanojevic G, Dojcinovic MP, Jankovic-Castvan I, Vujancevic JD, et al. Antioxidant and cell-friendly Fe2TiO5 nanoparticles for food packaging application. Food Chemistry. 2022;390. https://doi.org/10.1016/j.foodchem.2022.133198 Rizzotto F, Vasiljevic ZZ, Stanojevic G, Dojcinovic MP, Jankovic-Castvan I, Vujancevic JD, et al. Antioxidant and cell-friendly Fe2TiO5 nanoparticles for food packaging application. Food Chemistry. 2022;390. https://doi.org/10.1016/j.foodchem.2022.133198 Koshy RR, Reghunadhan A, Mary SK, Sadanandan S, Jose S, Thomas S, et al. AgNP anchored carbon dots and chitin nanowhisker embedded soy protein isolate films with freshness preservation for active packaging. Food Packaging and Shelf Life. 2022;33. https://doi.org/10.1016/j.fpsl.2022.100876 Koshy RR, Reghunadhan A, Mary SK, Sadanandan S, Jose S, Thomas S, et al. AgNP anchored carbon dots and chitin nanowhisker embedded soy protein isolate films with freshness preservation for active packaging. Food Packaging and Shelf Life. 2022;33. https://doi.org/10.1016/j.fpsl.2022.100876 Abdel Aziz MS, Salama HE. Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications. International Journal of Biological Macromolecules. 2022;212:294-302. https://doi.org/10.1016/j.ijbiomac.2022.05.107 Abdel Aziz MS, Salama HE. Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications. International Journal of Biological Macromolecules. 2022;212:294-302. https://doi.org/10.1016/j.ijbiomac.2022.05.107 Ran R, Chen S, Su Y, Wang L, He S, He B, et al. Preparation of pH-colorimetric films based on soy protein isolate/ZnO nanoparticles and grape-skin red for monitoring pork freshness. Food Control. 2022;137. https://doi.org/10.1016/j.foodcont.2022.108958 Ran R, Chen S, Su Y, Wang L, He S, He B, et al. Preparation of pH-colorimetric films based on soy protein isolate/ZnO nanoparticles and grape-skin red for monitoring pork freshness. Food Control. 2022;137. https://doi.org/10.1016/j.foodcont.2022.108958 Xu K, Mittal K, Ewald J, Rulli S, Jakubowski JL, George S, et al. Transcriptomic points of departure calculated from human intestinal cells exposed to dietary nanoparticles. Food and Chemical Toxicology. 2022;170. https://doi.org/10.1016/j.fct.2022.113501 Xu K, Mittal K, Ewald J, Rulli S, Jakubowski JL, George S, et al. Transcriptomic points of departure calculated from human intestinal cells exposed to dietary nanoparticles. Food and Chemical Toxicology. 2022;170. https://doi.org/10.1016/j.fct.2022.113501 Wang S, Kang X, Alenius H, Wong SH, Karisola P, El-Nezami H. Oral exposure to Ag or TiO2 nanoparticles perturbed gut transcriptome and microbiota in a mouse model of ulcerative colitis. Food and Chemical Toxicology. 2022;169. https://doi.org/10.1016/j.fct.2022.113368 Wang S, Kang X, Alenius H, Wong SH, Karisola P, El-Nezami H. Oral exposure to Ag or TiO2 nanoparticles perturbed gut transcriptome and microbiota in a mouse model of ulcerative colitis. Food and Chemical Toxicology. 2022;169. https://doi.org/10.1016/j.fct.2022.113368 Liu Y, Huang Y, Mou Z, Li R, Hossen A, Dai J, et al. Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee. Ecotoxicology and Environmental Safety. 2021;224. https://doi.org/10.1016/j.ecoenv.2021.112694 Liu Y, Huang Y, Mou Z, Li R, Hossen A, Dai J, et al. Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee. Ecotoxicology and Environmental Safety. 2021;224. https://doi.org/10.1016/j.ecoenv.2021.112694 Cornu R, Chrétien C, Pellequer Y, Martin H, Béduneau A. Small silica nanoparticles transiently modulate the intestinal permeability by actin cytoskeleton disruption in both Caco-2 and Caco-2/HT29-MTX models. Archives of Toxicology. 2020;94:1191-1202. https://doi.org/10.1007/s00204-020-02694-6 Cornu R, Chrétien C, Pellequer Y, Martin H, Béduneau A. Small silica nanoparticles transiently modulate the intestinal permeability by actin cytoskeleton disruption in both Caco-2 and Caco-2/HT29-MTX models. Archives of Toxicology. 2020;94:1191-1202. https://doi.org/10.1007/s00204-020-02694-6 Xu K, Basu N, George S. Dietary nanoparticles compromise epithelial integrity and enhance translocation and antigenicity of milk proteins: An in vitro investigation. NanoImpact. 2021;24. https://doi.org/10.1016/j.impact.2021.100369 Xu K, Basu N, George S. Dietary nanoparticles compromise epithelial integrity and enhance translocation and antigenicity of milk proteins: An in vitro investigation. NanoImpact. 2021;24. https://doi.org/10.1016/j.impact.2021.100369 Alaraby M, Annangi B, Hernández A, Creus A, Marcos R. A comprehensive study of the harmful effects of ZnO nanoparticles using Drosophila melanogaster as an in vivo model. Journal of Hazardous Materials. 2015;296:166-174. https://doi.org/10.1016/j.jhazmat.2015.04.053 Alaraby M, Annangi B, Hernández A, Creus A, Marcos R. A comprehensive study of the harmful effects of ZnO nanoparticles using Drosophila melanogaster as an in vivo model. Journal of Hazardous Materials. 2015;296:166-174. https://doi.org/10.1016/j.jhazmat.2015.04.053